DeFord Bailey (December 14, 1899 – July 2, 1982) was an American old-time musician and songwriter considered to be the first African American country music star. He started his career in the 1920s and was one of the first performers to be introduced on Nashville radio station WSM's Grand Ole Opry, and becoming, alongside Uncle Dave Macon, one of the program's most famous performers. He was the first African-American performer to appear on the show, and the first performer to record his music in Nashville. Bailey played several instruments in his career but is best known for playing the harmonica, often being referred to as a "harmonica wizard".

Bailey was born and raised in Tennessee, all his family played "black hillbilly" country and blues music and he learned how to play the harmonica and mandolin while recuperating from polio as a young child. He moved from New York to Nashville with relatives in his late teens and was a significant early contributor to Nashville's burgeoning music industry. Among the first generation of entertainers to perform live on the radio, his recorded compositions were well-known and popular.

Bailey toured and performed with Roy Acuff and many well-known country artists during the 1930s. But as a result of the 1941 royalties disagreement between Broadcast Music, Inc. (BMI) and American Society of Composers, Authors and Publishers (ASCAP), he was fired by WSM and stopped making his living as an entertainer. Afterwards, he supported himself and his family by opening a shoe shining company and renting out rooms in his home. He returned to sporadic public performances in 1974 when he was invited to participate in the Opry's first Old-Timers show and in 2005 was posthumously inducted into the Country Music Hall of Fame.