Rose Joan Blondell (August 30, 1906 – December 25, 1979) was an American actress who performed in film and television for 50 years.

Blondell began her career in vaudeville. After winning a beauty pageant, she embarked on a film career, establishing herself as a Pre-Code staple of Warner Bros. Pictures in wisecracking, sexy roles, appearing in more than 100 films and television productions. She was described as a "brassy blonde with a heart of gold." Blondell was most active in film during the 1930s and early 1940s, and during that time co-starred with Glenda Farrell, a colleague and close friend, in nine films. Blondell continued acting on film and television for the rest of her life, often in small, supporting roles. She was nominated for an Academy Award for Best Supporting Actress for her performance in The Blue Veil (1951). In 1958, she was nominated for the Tony Award for Best Featured Actress in a Play for her performance as Mrs. Farrow in The Rope Dancers.

Near the end of her life, Blondell was nominated for a Golden Globe for Best Supporting Actress for her performance in Opening Night (1977). She was featured in two more films, the blockbuster musical Grease (1978) and Franco Zeffirelli's The Champ (1979), which was released shortly before her death from leukemia.