The NBC Symphony Orchestra was a radio orchestra conceived by David Sarnoff, the president of the Radio Corporation of America, the parent corporation of the National Broadcasting Company especially for the conductor Arturo Toscanini. The NBC Symphony Orchestra performed weekly radio broadcast concerts with Toscanini and other conductors and several of its players served in the house orchestra for the NBC Radio Network. NBC encouraged the public’s perception of the Orchestra as a full-time organization exclusively at Toscanini’s beck and call, but Fortune disclosed in 1938 that these instrumentalists played other radio—and, later, television—broadcasts: “the Toscanini concerts have been allocated only fifteen of the thirty hours a week each man works, including rehearsals.”

The orchestra's first broadcast was on November 13, 1937, and it continued until disbanded in April 1954. A new ensemble, independent of the network, called the Symphony of the Air, followed. It was made up of former members of the NBC Symphony Orchestra and performed from 1954 to 1963, particularly under Leopold Stokowski.