James Melton (January 2, 1904 – April 21, 1961), a popular singer in the 1920s and early 1930s, later began a career as an operatic singer when tenor voices went out of style in popular music around 1932–35. His singing talent was similar to that of his contemporary Richard Crooks and baritones John Charles Thomas and Nelson Eddy, who sang popular music but also had operatic careers.

Melton usually catered to popular music fans, singing romantic songs and popular ballads in a sweet style. He was born in Moultrie, Georgia, but was raised in Citra, Florida, where his parents grew melons and handled hogs. Melton's father ran a sawmill in the time of history when sawmills were temporary tent buildings built near available lumber trees.

In 1920, he graduated from high school in Ocala, Florida, and then attended college at the University of Florida, Vanderbilt University, and the University of Georgia. He received vocal instruction from Gaetano de Luca in Nashville from 1923 to 1927 before moving to New York, where he studied with Beniamino Gigli's teacher, Enrico Rosati. Melton also worked in dance bands, playing saxophone in a college jazz ensemble and performing with Francis Craig's Orchestra in Atlanta in 1926.

In 1946, he was invited to sing "Back home again in Indiana" at the pre-race ceremonies of the Indianapolis 500 race. It was the first race after the world War II and the first time the song was performed.