| Seaberg (Seaburg), George | 1941 - 1950 | 48 | trumpet | |
| Seaberg, George | 1945 | 1 | trumpet | |
| Seaberg, George | 1929 | 2 | piano | |
| Seabra, Julio | 1912 | 1 | composer | |
| Seabrooke, Thomas Q. | 1904 | 5 | baritone vocal | |
| Seaburg, J.P. | 1935 | 1 | speaker | |
| Seaford, Dick | 1936 | 1 | composer | |
| Seagle, John | 1927 - 1940 | 46 | baritone vocal | |
| Seagle, Oscar | 1912 - 1926 | 131 | baritone vocal | |
| Seaglione, Charles | 1924 | 1 | composer | |
| Seago, Leon | 1940 | 2 | vocalist, composer, violin | |
| Seago, Leonard | 1942 | 24 | violin, vocalist, composer, lyricist, songwriter | |
| Sealby, Mabel | 1917 | 2 | soprano vocal | |
| Seale, Walter B. | 1924 - 1931 | 42 | baritone vocal, composer, arranger, songwriter | |
| Sealed Power Corporation | 1933 | 4 | sponsor | |
| Seals, Charles | 1956 | 1 | songwriter | |
| Seals, Herman "Baby" | 1957 | 2 | drums | |
| Seals, Jimmy | 1957 | 2 | saxophone | |
| Seals, Troy | 1947 - 1972 | 12 | guitar, electric guitar | |
| Seals, Warner | 1927 | 4 | clarinet, tenor saxophone | |
| Seaman, Bernie | 1926 - 1933 | 16 | songwriter, composer, lyricist | |
| Seaman, Gordon | 1948 | 6 | composer | |
| Seaman, Ruth M. | 1931 | 1 | soprano vocal | |
| Sean and the Brandywines | 1965 | 3 | Musical group | |
| Sean Nolan's Dublin Orchestra | 1926 - 1928 | 18 | Musical group | |
| Searcy Trio | 1926 | 2 | Musical group | |
| Searcy, Deloise | 1926 - 1927 | 34 | piano, leader, composer | |
| Searcy, George. See: Moran, George | | | See reference | |
| Searelle, Luscombe | 1906 - 1909 | 1 | composer, lyricist | |
| Searle, Jack | 1949 | 3 | vocalist | |
| Searls, W. K. | 1925 | 1 | saxophone | |
| Sears, Al | 1929 - 1957 | 99 | tenor saxophone, baritone saxophone, alto saxophone, saxophone, composer | |
| Sears, Albert Omega. See: Sears, Al | | | See reference | |
| Sears, Bertha G. | 1916 | 1 | vocalist | |
| Sears, Charles | 1933 - 1939 | 10 | tenor vocal | |
| Sears, Edmund Hamilton | 1914 - 1954 | 16 | lyricist | |
| Sears, Fred | 1949 | 8 | violin | |
| Sears, Gerald | 1927 | 2 | arranger | |
| Sears, Howard | 1930 | 4 | guitar, vocalist | |
| Sears, Jerry | 1932 - 1939 | 11 | piano, leader, composer, songwriter | |
| Sears, Kelly | 1930 | 4 | vocalist, banjo | |
| Sears, Zelda | 1924 | 1 | lyricist | |
| Seashore, Carl E. | 1939 | 9 | author | |
| Seaton, A. | 1937 - 1950 | 7 | vocalist | |
| Seattle Harmony Kings | 1925 - 1926 | 6 | Musical group | |
| Seaver, Blanche Ebert | 1926 - 1935 | 9 | composer, lyricist | |
| Seaver, Fred | 1916 | 1 | songwriter | |
| Seavey, Horace | 1926 | 14 | tuba | |
| Sebald, Alexander | 1928 | 10 | violin, arranger | |
| Sebastian | 1969 | 2 | performer | |
