Eddie Durham (August 19, 1906 – March 6, 1987) was an American musician, who pioneered the use of the electric guitar in jazz. He was a guitarist, trombonist, composer, and arranger for the orchestras of Bennie Moten, Jimmie Lunceford, and Count Basie.

With Edgar Battle he composed "Topsy", which was recorded by Count Basie and became a hit for Benny Goodman.

In 1938, Durham co-wrote "I Don't Want to Set the World on Fire", with Bennie Benjamin, Sol Marcus and Eddie Seiler. During the 1940s, Durham created Eddie Durham's All-Star Girl Orchestra, an African-American all female swing band that toured the United States and Canada.